Rolls And Rems, Lewisham
The shop is a just a breath away from chaotic, with a few large bins of super-cheap remnants at the front. Over the large ground floor there are a variety of fabrics at cheap to middling to reasonable prices, and a few special "expensive" fabrics (which are bargain-tastic compared to e.g. Berwick Street). This includes cotton, linen, poly-combo stuff, suit fabric, etc. The back of the shop has novelty fabrics such as monster fur and vinyl/tablecloth material.
The top floor is smaller and has lots of curtain fabric, blanket/quilting and sheet fabrics and some bridalwear type of things. On Bec's September 2007 visit there were also some Halloween themed fabrics (that I was told are there year round).
The shop also stocks a good supply of trimmings (zips, snaps, thread, elastic by the metre) and the staff are very eager to offer help and advice for any level of sewer.
Accessibility: No step to get in, and although the back of the ground floor is at a higher level there's a ramp to get up there. It is quite cramped inside, though. There also doesn't appear to be any step-free access to the top floor.